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I receive in Florence, Prato and Milan

Matteotti Medical Group
Viale Giacomo Matteotti, 42
50132 - Florence (FI)
Telephone: 055 570224
Florence Castello
Villa Donatello
Via Attilio Ragionieri, 101
50019 - Sesto Fiorentino (FI)
Telephone: 055 50975
Studi Medici Life
Viale della Repubblica, 141
59100 - Prato (PO)
Telephone: 0574 583501
Columbus Clinic Center
Via Michelangelo Buonarroti, 48
20145 - Milan (MI)
Telephone: 02 480 801

La Peyronie's disease

La Peyronie's disease Milan

Fighting la Peyronie’s disease Milan and the rest of the country has become easier today, thanks to the many specialized centers found in the Bel Paese. This condition, which leads to the well-known disease of the
curved penis
, afflicts about 7 percent of the Italian male population. Those most at risk are older men in the 50-70 age group.

La Peyronie’s Disease manifests as fibrous-cicatricial tissue at the corpora cavernosa of the penis. It was first observed in 1550 by an Italian, Antonio Vesalius. But it was not until 1743 that a first description of it could be had. Compiled by the French military doctor serving in the army of King Louis XV, François Gigot de La Peyronie, the condition acquired its very name.

Still the subject of numerous studies and research, the condition appears to result from trauma that the penis may have suffered during sexual intercourse, or in other accidental circumstances (work injuries, traffic accidents, sports injuries, etc…). Diagnosing it is rather easy, because its manifestation is obvious to the patient’s eyes, but the choice of which treatment to undergo is the sole prerogative of the treating urologist, or andrologist. This is because treatment must be chosen and proportionate according to the symptoms and the progress of the disease itself. Sometimes drug treatment may suffice, but in other cases something more invasive may be needed, such as, for example, surgery.

Peyronie's disease Milan: induratio penis plastica (PPI)

Peyronie’s disease is also called and known as Induratio penis plastica, abbreviated as PPI. It is an anatomical abnormality of the penis that manifests itself through the formation of fibrous-cicatricial tissue within the corpora cavernosa of the penis.

Because of this tissue, we slowly get to the formation of a real plaque that goes on to compromise the elasticity of the outer envelope of the penis, called the tunica albuginea. Thus, this pathology is one that causes the cavernous bodies of the penile structure to lose elasticity. The bodies are the structures that dilate by filling with blood during erection. When the fibrous-cicatricial tissue of la Peyronie’s disease forms, the bodies are crushed and consequently unable to fill with blood and thus lift the penis.

La Peyronie’s disease leads to the pathology of the curved penis, whereby the penis comes to assume a tilt, more or less pronounced that makes it difficult to perform a normal sexual act. The curvature that the penis goes into can be toward any direction: up, down, left and right. In some cases the inclination is so pronounced that it makes the sexual act painful, or even impossible.

What causes Peyronie's disease.

Studies and research have shown a close correlation between penile trauma and Peyronie’s disease. Traumatic origin can be attributed to traumatic events suffered by the penis during the sexual act, or due to traffic, sports, accidental, or workplace accidents. The creation of the fibrotic cluster is usually progressive, but it can also appear suddenly.

Beyond the trauma component, there are also several other risk factors to consider:

Peyronie's disease: how to diagnose it

Milan Peyronie’s disease is rather easy to diagnose because it is accompanied by symptoms that are also evident on an objective examination by the patient. First of all, a protuberance forms on the body of the penis that is also easily detectable by touch. In addition, during erection, the patient will feel pain, reduction in the normal length of the penis, and especially abnormal curvature.

Several complications at this point:

Beyond the trauma component, there are also several other risk factors to consider:

The andrologist may request that an ultrasound be performed to be able to better identify the exact location of the fibrous-cystic plaque.

Treatments and cures

Treatments to counter and cure Peyronie’s disease can be:

  • pharmacological
  • surgical

Pharmacology is used when penile curvature is not excessive and symptoms are mild to moderate.

In this case, administration by injection of Collagenase from Clostridium histolyticum. La collagenesis is a particular enzyme that can break down collagen into small pieces. In fact, it is collagen that plays a major role in the formation of fibrous-cytial tissue. Injections of Collagenase of Clostridium histolyticum thus help to significantly improve penile curvature, without surgery, in a noninvasive way. The results are excellent and the contraindications virtually nonexistent. Usually local anesthesia is given before the injection.


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    I receive at and Facilities in Milan, Florence, Prato.

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    Florence | Matteotti Medical Group

    Giacomo Matteotti Avenue, 42
    50132 – Florence (FI)
    Phone: 055 570224

    Florence Castle | Villa Donatello

    Attilio Ragionieri Street, 101
    50019 – Sesto Fiorentino (FI)
    Phone: 055 50975

    Prato | Life Medical Practice

    141 Republic Avenue
    59100 – Prato (PO)
    Phone: 0574 583501

    Milan | Columbus Clinic Center

    Via Michelangelo Buonarroti, 48
    20145 – Milan (MI)
    Phone: 02 480801

    Dr. Andrea Cocci

    urologist and andrologist

    The choice to devote my professional life to urology and in particular to andrologic and reconstructive surgery is the result of a deep passion for anatomy, the art of surgery and in general the diagnostic therapeutic process leading to patient recovery. Oncological pathology, infertility, erectile dysfunction, penile disease, or simply prostate disorders irretrievably afflict not only the individual but also the couple dimension.

    Received at:
    Florence, Milan, Prato

    Dr. Andrea Cocci
    Urologist and andrologist

    I have full conviction that listening to the patient, carping about his or her needs, and assessing his or her expectations is the only way to establish a therapeutic program of success and satisfaction for both physician and patient.